Gene: DTX3L
Official Full Name: deltex E3 ubiquitin ligase 3Lprovided by HGNC
Gene Summary: Enables several functions, including STAT family protein binding activity; histone H4K91 ubiquitin ligase activity; and protein ADP-ribosyltransferase-substrate adaptor activity. Involved in several processes, including positive regulation of protein localization; protein ubiquitination; and regulation of macromolecule metabolic process. Located in several cellular components, including early endosome; lysosome; and nucleoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01336 | DTX3L Knockout cell line (HUVEC) | Human | DTX3L | 1:2-1:3 | Negative | Online Inquiry |
KO11416 | DTX3L Knockout cell line (HeLa) | Human | DTX3L | 1:3~1:6 | Negative | Online Inquiry |
KO11417 | DTX3L Knockout cell line (HCT 116) | Human | DTX3L | 1:2~1:4 | Negative | Online Inquiry |
KO11418 | DTX3L Knockout cell line (HEK293) | Human | DTX3L | 1:3~1:6 | Negative | Online Inquiry |
KO11419 | DTX3L Knockout cell line (A549) | Human | DTX3L | 1:3~1:4 | Negative | Online Inquiry |
DTX3L Gene Knockout Cell Lines represent a significant advancement in the study of gene function and cellular mechanisms. These cell lines are genetically modified to permanently disable the DTX3L gene, offering researchers a valuable tool to explore the biological pathways in which this gene is involved. DTX3L is implicated in various cellular processes, including apoptosis and the modulation of protein interactions, making its knockout pivotal for understanding disease states and cellular responses.
The key function of DTX3L Gene Knockout Cell Lines lies in their ability to facilitate targeted investigations into gene function through loss-of-function studies. By effectively eliminating DTX3L expression, these cell lines allow for the assessment of downstream effects on cell proliferation, differentiation, and signal transduction pathways. Researchers can employ these cells to model pathological conditions, including certain cancers and neurodegenerative diseases, enabling more accurate recapitulation of the biological variations pertinent to these disorders.
Scientifically, the DTX3L knockout cell lines are indispensable in both basic and applied research settings. In clinical and translational research, they serve as a backbone for drug discovery efforts, providing a clearer understanding of molecular targets and therapeutic avenues. Additionally, their role in elucidating gene functions directly correlates with advancements in gene therapy and precision medicine.
The advantages of our DTX3L Gene Knockout Cell Lines extend beyond typical alternatives. Unlike transient knockdown approaches that may yield temporary or inconsistent results, the stable knockout guarantees reproducibility and reliability over extended study periods. This inherent stability allows researchers to conduct long-term experiments with confidence, further underlined by the robust data supporting cellular behavior under varying experimental conditions.
For researchers and clinicians aiming to dissect complex biological networks or develop innovative therapeutic strategies, the DTX3L Gene Knockout Cell Lines are an essential resource. Their application in gene function analysis, drug testing, and disease modeling emphasizes their irreplaceable value in advancing scientific knowledge and promoting therapeutic breakthroughs.
At [Your Company Name], our commitment to quality and innovation stems from years of expertise in genetic engineering and cellular biology. We understand the critical demands of research settings and strive to provide resources that facilitate cutting-edge discoveries and advancements in health and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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