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DAZAP2 Knockout Cell Lines

Gene: DAZAP2

Official Full Name: DAZ associated protein 2provided by HGNC

Gene Summary: This gene encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05872 DAZAP2 Knockout cell line (HeLa) Human DAZAP2 1:3~1:6 Negative Online Inquiry
KO05873 DAZAP2 Knockout cell line (HCT 116) Human DAZAP2 1:2~1:4 Negative Online Inquiry
KO05874 DAZAP2 Knockout cell line (HEK293) Human DAZAP2 1:3~1:6 Negative Online Inquiry
KO05875 DAZAP2 Knockout cell line (A549) Human DAZAP2 1:3~1:4 Negative Online Inquiry

Background

DAZAP2 Gene Knockout Cell Lines are genetically modified cell lines designed to facilitate the study of the DAZAP2 gene and its biological functions. These cell lines are created using cutting-edge CRISPR-Cas9 technology to disrupt the DAZAP2 gene, providing researchers with a powerful tool to investigate the role of this gene in cellular processes, including gene expression regulation, RNA-mediated pathways, and developmental biology.

By producing a loss-of-function model, DAZAP2 Gene Knockout Cell Lines enable scientists to discern the phenotypic consequences of DAZAP2 deficiency. This product’s mechanisms rest on the ability to generate specific mutations within the gene, thereby allowing comprehensive analyses of its functions in vitro. Researchers can assess changes in proliferation, differentiation, and response to external stimuli, thus elucidating the gene's involvement in various cellular and pathological processes.

The scientific importance of DAZAP2 Gene Knockout Cell Lines extends to a myriad of applications in both basic and applied research, including cancer studies, neurobiology, and genetic disorder investigations. Understanding the impact of DAZAP2 on cellular mechanisms can reveal insights pertinent to diseases such as neurodegeneration or oncogenesis, thereby fostering advancements in therapeutic strategies.

What sets DAZAP2 Gene Knockout Cell Lines apart from alternative models is their high specificity and efficiency in gene editing, leading to consistent and reproducible results across different experiments. Furthermore, these cell lines are readily available and compatible with various experimental conditions, ensuring ease of integration into existing research workflows.

For researchers and clinicians, DAZAP2 Gene Knockout Cell Lines offer unparalleled value by providing robust models for the investigation of genetic and molecular pathways. This product empowers users to advance their discoveries and may contribute to the development of novel therapeutic interventions.

Our company prides itself on its expertise in genetic engineering and cell line development. We are committed to supplying high-quality biological products that empower the scientific community to achieve groundbreaking innovations.

Please note that all services are for research use only. Not intended for any clinical use.

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