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CYB5D2 Knockout Cell Lines

Gene: CYB5D2

Official Full Name: cytochrome b5 domain containing 2provided by HGNC

Gene Summary: Predicted to enable heme binding activity. Predicted to be involved in nervous system development. Predicted to act upstream of or within positive regulation of neuron differentiation. Predicted to be located in extracellular region. Predicted to be active in endomembrane system and membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27868 CYB5D2 Knockout cell line (HeLa) Human CYB5D2 1:3~1:6 Negative Online Inquiry
KO27869 CYB5D2 Knockout cell line (HCT 116) Human CYB5D2 1:2~1:4 Negative Online Inquiry
KO27870 CYB5D2 Knockout cell line (HEK293) Human CYB5D2 1:3~1:6 Negative Online Inquiry
KO27871 CYB5D2 Knockout cell line (A549) Human CYB5D2 1:3~1:4 Negative Online Inquiry

Background

CYB5D2 Gene Knockout Cell Lines are specifically engineered cellular models designed to lack the functional CYB5D2 gene, which encodes for cytochrome b5 domain containing 2, a protein involved in various metabolic processes, including lipid metabolism and drug metabolism. These cell lines are generated using advanced CRISPR/Cas9 technology, ensuring precise genomic alterations that enable researchers to study the functional consequences of CYB5D2 deficiency with high specificity and reproducibility.

The primary function of these knockout cell lines is to elucidate the biological roles of CYB5D2 in cellular metabolism and signaling pathways. By removing the CYB5D2 gene, researchers can investigate its implications in various physiological processes such as fatty acid elongation and the metabolism of xenobiotics, which plays a critical role in pharmacology and toxicology studies. This enables a deeper understanding of how disturbances in cytochrome b5 function may influence metabolic diseases and drug responses.

Scientifically, CYB5D2 Gene Knockout Cell Lines have significant applications in both basic research and clinical settings. They serve as valuable platforms for drug discovery, allowing scientists to screen potential therapeutics and assess their efficacy. Additionally, they can provide insights into metabolic disorders, paving the way for targeted gene therapies and personalized medicine strategies.

Unlike traditional cell lines that may express varying levels of CYB5D2, our gene knockout lines offer a consistent and clear model for experimentation, thereby reducing variability and enhancing the reliability of data. This specificity is vital for obtaining accurate insights, especially in high-stakes research environments where reproducibility is paramount.

The value of CYB5D2 Gene Knockout Cell Lines lies in their potential to transform our understanding of metabolic regulation and therapeutic interventions. For researchers and clinical practitioners alike, these cell lines represent an innovative tool that can elucidate mechanisms of disease and contribute to the development of effective treatments.

Our company prides itself on its commitment to providing high-quality, cutting-edge biological products that facilitate groundbreaking research. With expertise in genomic engineering and a focus on innovation, we are dedicated to supporting scientists in their quest to advance knowledge and improve health outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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