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CUX1 Knockout Cell Lines

Gene: CUX1

Official Full Name: cut like homeobox 1provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38329 CUX1 Knockout cell line (HeLa) Human CUX1 1:3~1:6 Negative Online Inquiry
KO38330 CUX1 Knockout cell line (HCT 116) Human CUX1 1:2~1:4 Negative Online Inquiry
KO38331 CUX1 Knockout cell line (HEK293) Human CUX1 1:3~1:6 Negative Online Inquiry
KO38332 CUX1 Knockout cell line (A549) Human CUX1 1:3~1:4 Negative Online Inquiry

Background

CUX1 Gene Knockout Cell Lines are specialized cell cultures engineered to lack the expression of the CUX1 gene, a crucial regulator in cellular processes such as proliferation, differentiation, and survival. By utilizing CRISPR/Cas9 gene-editing technology, these cell lines enable researchers to study the effects of CUX1 loss on various signaling pathways and cellular functions. This knockout model is essential for dissecting the genetic underpinnings of diseases where the CUX1 gene plays a pivotal role, including certain cancer types and developmental disorders.

The primary function of CUX1, which encodes a transcription factor, involves mediating gene expression regulation in response to environmental cues. By disrupting CUX1 expression, these cell lines allow scientists to explore alternative pathways that may be activated in the absence of this transcription factor, providing insights into tumorigenesis and other pathological states. In research settings, these knockout cell lines are invaluable for functional genomics studies, drug discovery, and development of targeted therapies.

One of the striking advantages of CUX1 Gene Knockout Cell Lines compared to conventional knockdown methods is the permanence of the knockout, which leads to stable cellular changes that can be reliably studied over time. This stability, combined with the ease of use of CRISPR/Cas9, presents researchers with a powerful tool for creating reproducible experimental models.

For clinicians and investigators, the availability of CUX1 Gene Knockout Cell Lines represents a significant resource for accelerating the understanding of cancer biology and potentially identifying new therapeutic targets. By bridging the gap between laboratory research and clinical application, these cell lines serve as a pivotal element in advancing personalized medicine approaches.

Our company is dedicated to providing high-quality biological products designed to enhance research and clinical insights. With a strong foundation in genetic engineering and cell biology, we ensure that our CUX1 Gene Knockout Cell Lines not only meet but exceed scientific standards, empowering researchers in their pursuit of groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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