Gene: CPZ
Official Full Name: carboxypeptidase Zprovided by HGNC
Gene Summary: This gene encodes a member of the metallocarboxypeptidase family. This enzyme displays carboxypeptidase activity towards substrates with basic C-terminal residues. It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34086 | CPZ Knockout cell line (HEK293) | Human | CPZ | 1:3~1:6 | Negative | Online Inquiry |
CPZ Gene Knockout Cell Lines are genetically engineered cellular models designed to specifically disable the CPZ gene, resulting in the complete absence of its encoded protein. This innovative tool allows researchers to study the biological consequences of CPZ gene disruption in a controlled environment, providing insights into cellular pathways, gene function, and disease mechanisms.
The primary function of CPZ Gene Knockout Cell Lines is to facilitate the dissection of gene function by providing a clean background devoid of the endogenous CPZ protein. By using techniques such as CRISPR-Cas9 genome editing, these cell lines allow for precise alterations, enabling the study of downstream effects and compensatory mechanisms that may arise from gene knockout. Researchers can analyze changes in cellular behavior such as proliferation, differentiation, and response to stimuli, which can be pivotal in understanding various biological processes and disease states, including neurodegenerative disorders.
The scientific importance of these cell lines is underscored by their applications in both basic research and preclinical studies. They serve as essential models for drug development, enabling the exploration of therapeutic targets and the validation of novel compounds. Additionally, the ability to create specific gene knockouts can facilitate research into diseases where CPZ plays a critical role, thus driving forward our understanding in fields such as oncology and developmental biology.
Compared to alternative models, CPZ Gene Knockout Cell Lines are uniquely valuable due to their robust nature and the simplification they provide in complex genetic studies. Their generation is tailored to preserve cellular characteristics, allowing for accurate modeling of physiological conditions. Moreover, these knockout lines eliminate off-target effects commonly observed in traditional RNA interference methods, which enhances the reliability of experimental outcomes.
These cell lines offer significant value for researchers and clinicians alike, serving as a vital resource for advancing scientific inquiry and therapeutic development. By providing a reliable platform to interrogate gene function, they empower users to uncover novel insights that can lead to innovative treatments and therapies.
Our company specializes in the creation and distribution of high-quality biological products, leveraging our deep expertise in genetic engineering and cell culture methodologies. Committed to advancing research and innovation, we provide essential tools that drive scientific progress and facilitate breakthroughs in understanding complex biological systems.
Please note that all services are for research use only. Not intended for any clinical use.
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CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.