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CORO1B Knockout Cell Lines

Gene: CORO1B

Official Full Name: coronin 1Bprovided by HGNC

Gene Summary: Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29080 CORO1B Knockout cell line (HeLa) Human CORO1B 1:3~1:6 Negative Online Inquiry
KO29081 CORO1B Knockout cell line (HCT 116) Human CORO1B 1:2~1:4 Negative Online Inquiry
KO29082 CORO1B Knockout cell line (HEK293) Human CORO1B 1:3~1:6 Negative Online Inquiry
KO29083 CORO1B Knockout cell line (A549) Human CORO1B 1:3~1:4 Negative Online Inquiry

Background

CORO1B Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the functions of the CORO1B gene, which encodes a protein integral to various cellular processes, including cytoskeletal dynamics, cell motility, and immune responses. By employing the CRISPR-Cas9 gene editing technology, these cell lines feature a complete knockout of the CORO1B gene, allowing researchers to systematically analyze the downstream effects of its absence and gain insights into its role in physiological and pathological conditions.

The primary function of CORO1B involves regulating actin filament assembly and disassembly, crucial for cellular movement and maintaining the structural integrity of cells. Researchers using these knockout models can investigate how the loss of CORO1B impacts processes such as phagocytosis in immune cells or the metastasis of cancer cells, thus providing a clearer understanding of disease mechanisms. These cell lines serve as a powerful tool for both basic research and translational studies, facilitating the development of targeted therapeutic strategies.

One significant advantage of the CORO1B Gene Knockout Cell Lines is the precision of the CRISPR-Cas9 technology, which allows for specific and efficient gene editing without the off-target effects commonly seen with traditional methods. Compared to alternative models, these knockout cell lines provide a more accurate representation of the functional absence of the gene in question.

The value of CORO1B Gene Knockout Cell Lines is immense for researchers and clinicians alike, as they enable a deeper exploration of the biological relevance of the CORO1B protein in health and disease. By utilizing these cell lines, scientists can not only contribute to fundamental cellular biology but also provide crucial insights that may lead to advancements in drug development and personalized medicine.

Our company is committed to advancing scientific research by offering high-quality biological products, and the CORO1B Gene Knockout Cell Lines exemplify our dedication to supporting innovative research in the life sciences. With a strong focus on reliability and precision, our products empower researchers to achieve groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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