Gene: CLMP
Official Full Name: CXADR like membrane proteinprovided by HGNC
Gene Summary: This gene encodes a type I transmembrane protein that is localized to junctional complexes between endothelial and epithelial cells and may have a role in cell-cell adhesion. Expression of this gene in white adipose tissue is implicated in adipocyte maturation and development of obesity. This gene is also essential for normal intestinal development and mutations in the gene are associated with congenital short bowel syndrome. [provided by RefSeq, Aug 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20615 | CLMP Knockout cell line (HeLa) | Human | CLMP | 1:3~1:6 | Negative | Online Inquiry |
KO20616 | CLMP Knockout cell line (HCT 116) | Human | CLMP | 1:2~1:4 | Negative | Online Inquiry |
KO20617 | CLMP Knockout cell line (A549) | Human | CLMP | 1:3~1:4 | Negative | Online Inquiry |
CLMP Gene Knockout Cell Lines are specialized cellular models engineered to lack the CLMP (Carcinoembryonic Antigen-Related Cell Adhesion Molecule) gene, allowing researchers to investigate the role of this gene in various biological processes. These cell lines are invaluable for studying cellular adhesion, migration, and signaling pathways that are critical in cancer research and developmental biology.
The mechanism of function operates through the complete elimination of the CLMP gene, effectively removing its encoded protein from the cell environment. This knockout provides a platform for understanding the implications of loss-of-function mutations in gene regulation, as well as their downstream biochemical effects. Researchers can utilize these cell lines to observe changes in cellular behavior, assess alternative pathways activated in the absence of CLMP, and identify potential therapeutic targets.
The scientific importance of CLMP Gene Knockout Cell Lines is significant, especially in research settings focused on tumorigenesis, inflammation, and immune response modulation. By shedding light on the precise roles of CLMP, researchers can better comprehend its contribution to disease processes, paving the way for potential therapeutic interventions.
Compared to traditional cell lines, these knockout models offer a clear advantage by minimizing confounding variables, enabling more straightforward interpretations of experimental results. Their high reproducibility and ease of use position them as superior choices for researchers aiming to develop targeted therapies or investigate gene function.
In essence, CLMP Gene Knockout Cell Lines represent a critical tool in advancing our understanding of gene function in health and disease. For researchers and clinicians alike, harnessing the unique capabilities of these specialized cell lines can accelerate discoveries and inform treatment strategies. With years of expertise in developing cutting-edge biological products, our company is dedicated to equipping the scientific community with essential tools that drive innovation and improve outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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