Gene: CLIP1
Official Full Name: CAP-Gly domain containing linker protein 1provided by HGNC
Gene Summary: The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09155 | CLIP1 Knockout cell line (HeLa) | Human | CLIP1 | 1:3~1:6 | Negative | Online Inquiry |
KO09156 | CLIP1 Knockout cell line (HCT 116) | Human | CLIP1 | 1:2~1:4 | Negative | Online Inquiry |
KO09157 | CLIP1 Knockout cell line (HEK293) | Human | CLIP1 | 1:3~1:6 | Negative | Online Inquiry |
KO09158 | CLIP1 Knockout cell line (A549) | Human | CLIP1 | 1:3~1:4 | Negative | Online Inquiry |
CLIP1 Gene Knockout Cell Lines are engineered cellular models designed to elucidate the role of the CLIP1 gene in various biological processes. CLIP1, or CAP-GLY domain containing linker protein 1, is involved in the transport of cellular components, playing a significant role in the dynamics of the cytoskeleton. The CLIP1 Gene Knockout Cell Lines employ CRISPR-Cas9 technology to knock out the CLIP1 gene, allowing researchers to study its functions by observing the physiological and molecular changes that occur in its absence.
These cell lines facilitate a range of research applications, particularly in neurobiology and cancer. By utilizing the CLIP1 Gene Knockout Cell Lines, scientists can investigate the implications of disrupted cytoskeletal transport, which is pivotal for cellular motility, division, and neuronal function. The ability to perform loss-of-function studies enhances the understanding of diseases linked to cytoskeletal abnormalities, thus contributing valuable insights for potential therapeutic targets.
What distinguishes CLIP1 Gene Knockout Cell Lines from other cellular models is the specificity and precision achieved through CRISPR technology. Traditional knockout methods, such as those involving homologous recombination, can be cumbersome and less efficient. In contrast, our cell lines are rigorously validated to ensure that the knockout is complete, minimizing off-target effects and variability. Additionally, they are conveniently available in multiple backgrounds, enabling researchers to select the most appropriate model for their study.
For researchers and clinicians, the ability to characterize the role of CLIP1 provides essential data for advancing understanding of complex biological phenomena and mechanisms underpinning various diseases. This product offers a robust platform for high-impact studies, driving innovation in therapeutic development.
With our expertise in genetic engineering and commitment to providing high-quality biological products, we guarantee that our CLIP1 Gene Knockout Cell Lines are manufactured under stringent quality controls, ensuring that researchers receive reliable and reproducible results for their scientific investigations.
Please note that all services are for research use only. Not intended for any clinical use.
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