Gene: CHCHD7
Official Full Name: coiled-coil-helix-coiled-coil-helix domain containing 7provided by HGNC
Gene Summary: Predicted to be involved in mitochondrial respiratory chain complex assembly. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18740 | CHCHD7 Knockout cell line (HeLa) | Human | CHCHD7 | 1:3~1:6 | Negative | Online Inquiry |
KO18741 | CHCHD7 Knockout cell line (HCT 116) | Human | CHCHD7 | 1:2~1:4 | Negative | Online Inquiry |
KO18742 | CHCHD7 Knockout cell line (HEK293) | Human | CHCHD7 | 1:3~1:6 | Negative | Online Inquiry |
KO18743 | CHCHD7 Knockout cell line (A549) | Human | CHCHD7 | 1:3~1:4 | Negative | Online Inquiry |
CHCHD7 Gene Knockout Cell Lines are genetically modified cell lines designed to specifically disrupt the CHCHD7 gene, which is involved in critical cellular processes such as mitochondrial function, cellular redox homeostasis, and stress response. These unique cell lines serve as pivotal tools for researchers investigating the biological roles of CHCHD7 in various physiological and pathological contexts, including neurodegenerative diseases and cancer.
The primary function of CHCHD7 knockout cell lines is to facilitate the study of gene function by effectively eliminating the expression of the CHCHD7 protein. This gene knockout can be achieved through techniques such as CRISPR-Cas9 or RNA interference, leading to altered cellular behavior and providing insights into CHCHD7's role in mitochondrial dynamics and cellular metabolism. By understanding these mechanisms, researchers can elucidate the molecular pathways that contribute to disease progression and identify potential therapeutic targets.
The scientific significance of these cell lines resides in their application in both basic and applied research settings. In clinical research, CHCHD7 knockout cell lines can be instrumental in drug discovery efforts, allowing scientists to identify compounds that may restore mitochondrial function or mitigate stress responses. Furthermore, these models can be used to study the effects of genetic modulation on various cell types, thereby expanding the understanding of CHCHD7-related pathologies.
What sets our CHCHD7 Gene Knockout Cell Lines apart from alternatives is their robust validation and reproducibility, backed by extensive characterization data. These lines are produced utilizing rigorous quality control protocols ensuring consistent performance across experiments, which is vital for generating reliable data. Additionally, our cell lines come with comprehensive technical support, enabling users to maximize their research outcomes.
By investing in our CHCHD7 Gene Knockout Cell Lines, researchers and clinicians gain access to high-quality, scientifically validated tools that enhance their ability to explore gene function and its implications in health and disease. Our commitment to delivering advanced biological products is reinforced by a team of experts dedicated to facilitating scientific discovery and innovation in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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