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CEMIP Knockout Cell Lines

Gene: CEMIP

Official Full Name: cell migration inducing hyaluronidase 1provided by HGNC

Gene Summary: Enables several functions, including clathrin heavy chain binding activity; hyaluronic acid binding activity; and hyalurononglucosaminidase activity. Involved in several processes, including hyaluronan catabolic process; positive regulation of protein phosphorylation; and positive regulation of protein targeting to membrane. Located in several cellular components, including clathrin-coated endocytic vesicle; endoplasmic reticulum; and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20303 CEMIP Knockout cell line (HCT 116) Human CEMIP 1:2~1:4 Negative Online Inquiry
KO20304 CEMIP Knockout cell line (HEK293) Human CEMIP 1:3~1:6 Negative Online Inquiry

Background

CEMIP Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the function of the CEMIP (Cell Migration-Inducing Hyaluronan-Binding Protein) gene. These cell lines facilitate the exploration of CEMIP's critical role in cellular processes, particularly in cancer progression, inflammation, and tissue remodeling. By providing researchers with a system where the CEMIP gene is disrupted, these knockout lines enable detailed assessments of how the absence of CEMIP influences cellular behavior and molecular pathways.

The key functions of CEMIP involve its interactions with hyaluronan and its involvement in various signaling cascades that affect cell migration and proliferation. By knocking out this gene, scientists can elucidate CEMIP's contributions to tumor microenvironments and its potential as a therapeutic target. Studies utilizing these knockout cell lines can lead to significant insights into the mechanisms of metastasis and the therapeutic targeting of CEMIP may offer new avenues for clinical intervention in aggressive cancers.

From a scientific perspective, CEMIP Gene Knockout Cell Lines hold immense value, particularly in cancer biology, developmental biology, and regenerative medicine. Their ability to mimic disease states accurately makes them indispensable in preclinical research, allowing for the investigation of gene function and drug response without the confounding variables present in wild-type models.

Compared to alternative products, the CEMIP Gene Knockout Cell Lines stand out due to their reliability, high customization potential, and comprehensive characterization. Researchers benefit from an optimized workflow that includes validated genetic modifications, resulting in reproducible and reliable experimental outcomes.

The value of CEMIP Gene Knockout Cell Lines extends beyond research, providing clinical researchers and pharmaceutical companies with the tools necessary for developing novel therapeutics and diagnostic approaches. By leveraging these models, users can streamline their studies, enhance the translational potential of their findings, and ultimately advance the understanding and treatment of diseases involving the CEMIP pathway.

Our company specializes in producing high-quality genetic models, backed by years of development and expertise in cellular engineering. We are committed to providing researchers and clinicians with innovative tools that support groundbreaking discoveries and improve health outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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