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CD164 Knockout Cell Lines

Gene: CD164

Official Full Name: CD164 moleculeprovided by HGNC

Gene Summary: This gene encodes a transmembrane sialomucin and cell adhesion molecule that regulates the proliferation, adhesion and migration of hematopoietic progenitor cells. The encoded protein also interacts with the C-X-C chemokine receptor type 4 and may regulate muscle development. Elevated expression of this gene has been observed in human patients with Sezary syndrome, a type of blood cancer, and a mutation in this gene may be associated with impaired hearing. [provided by RefSeq, Oct 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00223 CD164 Knockout cell line (A549) Human CD164 1:3~1:4 Negative Online Inquiry
KO33881 CD164 Knockout cell line (HeLa) Human CD164 1:3~1:6 Negative Online Inquiry
KO33882 CD164 Knockout cell line (HCT 116) Human CD164 1:2~1:4 Negative Online Inquiry
KO33883 CD164 Knockout cell line (HEK293) Human CD164 1:3~1:6 Negative Online Inquiry

Background

CD164 Gene Knockout Cell Lines are precisely engineered cellular models designed to facilitate the detailed study of the CD164 gene’s role in various biological processes. CD164, also known as the sialomucin CD164, plays a critical role in cell adhesion, migration, and hematopoiesis. The knockout of this gene creates a robust platform to explore the implications of CD164 in immunological responses, cancer progression, and stem cell differentiation.

These cell lines function through the insertion of targeted genetic modifications that disrupt the CD164 gene, effectively allowing researchers to observe phenotypic and functional changes stemming from the absence of this important gene. The mechanisms at play involve the downregulation of associated signaling pathways which are essential for cellular interactions and can influence various physiological responses.

The scientific importance of CD164 Gene Knockout Cell Lines extends into both research and clinical applications; they serve as valuable tools for elucidating the gene's intricate involvement in disease mechanisms and developing potential therapeutic strategies. Their use can also help uncover novel biomarkers for disease diagnosis and prognosis.

What sets our CD164 Gene Knockout Cell Lines apart from alternative products is the precision of our gene-editing technology, which ensures high efficiency and specificity in gene disruption. Additionally, our cell lines are rigorously validated for consistent performance and reproducibility across experiments, reducing variability and enhancing the reliability of research outcomes.

For researchers and clinicians, the value of using these engineered cells lies in their ability to provide a clearer understanding of underlying biological pathways, thus driving innovations in medical research and potential treatment modalities.

Our company prides itself on its commitment to advancing biological research through high-quality, genetically modified models. Leveraging extensive expertise in genetic engineering and cell culture techniques, we deliver exceptional products designed to meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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