Gene: CCDC61
Official Full Name: coiled-coil domain containing 61provided by HGNC
Gene Summary: Enables identical protein binding activity and microtubule binding activity. Involved in centriole assembly and mitotic spindle assembly. Located in centriolar satellite and ciliary basal body. Part of centriolar subdistal appendage. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19010 | CCDC61 Knockout cell line (HeLa) | Human | CCDC61 | 1:3~1:6 | Negative | Online Inquiry |
KO19011 | CCDC61 Knockout cell line (HCT 116) | Human | CCDC61 | 1:2~1:4 | Negative | Online Inquiry |
KO19012 | CCDC61 Knockout cell line (HEK293) | Human | CCDC61 | 1:3~1:6 | Negative | Online Inquiry |
KO19013 | CCDC61 Knockout cell line (A549) | Human | CCDC61 | 1:3~1:4 | Negative | Online Inquiry |
CCDC61 Gene Knockout Cell Lines are a meticulously engineered tool tailored for advanced research in cellular biology and gene function analysis. These cell lines feature a complete knockout of the CCDC61 gene, which encodes a cytoplasmic protein implicated in various cellular processes, including regulation of cellular architecture and signaling pathways. By eliminating the expression of this gene, researchers can effectively investigate the phenotypic consequences in cellular behavior, providing insights into its biological role and implications in health and disease.
The primary function of these knockout cell lines is to facilitate the study of gene function through loss-of-function analysis. By comparing the CCDC61 gene knockout cells to their wild-type counterparts, researchers can observe differences in proliferation, differentiation, apoptosis, and response to environmental stimuli. This mechanistic understanding is critical for elucidating the role of CCDC61 in contexts such as cancer progression, metabolic disorders, and neurodegenerative diseases.
From a scientific standpoint, CCDC61 Gene Knockout Cell Lines serve as a vital resource in both fundamental research and translational applications. They are particularly valuable for studying disease mechanisms and for the development of therapeutic strategies involving gene therapy or targeted treatments. Furthermore, the availability of these cell lines accelerates the drug discovery process by enabling high-throughput screening of compound efficacy and toxicity.
Distinct from traditional genetic manipulation methods, such as plasmid-based overexpression systems, these knockout lines provide a clean, stable model that eliminates confounding variability found in transient systems. This irreversible gene disruption eliminates off-target effects typical of alternative approaches, ensuring that findings are both reproducible and reliable.
For researchers and clinicians alike, the availability of CCDC61 Gene Knockout Cell Lines represents an essential advancement in the toolkit for genetic and molecular biology research. Their precise design and robust stability make them a powerful asset in elucidating gene function and developing novel therapeutic avenues.
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Please note that all services are for research use only. Not intended for any clinical use.
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