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CANT1 Knockout Cell Lines

Gene: CANT1

Official Full Name: calcium activated nucleotidase 1provided by HGNC

Gene Summary: This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05326 CANT1 Knockout cell line (HeLa) Human CANT1 1:3~1:6 Negative Online Inquiry
KO05327 CANT1 Knockout cell line (HCT 116) Human CANT1 1:2~1:4 Negative Online Inquiry
KO05328 CANT1 Knockout cell line (HEK293) Human CANT1 1:3~1:6 Negative Online Inquiry
KO05329 CANT1 Knockout cell line (A549) Human CANT1 1:3~1:4 Negative Online Inquiry

Background

CANT1 Gene Knockout Cell Lines are specialized cell culture models generated to effectively investigate the role of the CANT1 gene, which encodes the enzyme Calcium-activated nucleotidase 1. These knockout cell lines facilitate functional studies by providing a platform for examining the physiological and pathological implications of CANT1 deficiency, as well as its potential involvement in various diseases, including certain forms of developmental disorders and cancers.

These cell lines operate on the principle of gene editing technologies, most notably CRISPR-Cas9, which allows for precise alterations in the genome. By creating a targeted deletion of the CANT1 gene, researchers can assess the resulting phenotypic changes, cellular signaling pathways, and interactions with other genes. This provides invaluable insights into how CANT1 contributes to metabolic processes and cellular homeostasis.

The scientific importance of CANT1 Gene Knockout Cell Lines lies in their ability to uncover the complexities of nucleotide metabolism and its implications in both fundamental biology and translational medicine. These models serve as critical tools for drug discovery, biomarker identification, and preclinical evaluation of therapeutics targeting CANT1-associated pathways. Their applications extend to genetic research, where understanding the gene's function can lead to revealing mechanisms behind various genetic disorders.

Compared to alternative models, CANT1 Gene Knockout Cell Lines offer enhanced specificity, resulting from the complete absence of the CANT1 protein, which facilitates clearer observation of the gene's effects without confounding variables. Additionally, they provide researchers with a reliable and reproducible tool, significantly boosting experimental rigor and reliability.

For researchers and clinicians, these cell lines are indispensable for detailed mechanistic studies, offering a robust platform that streamlines the investigation of CANT1's role in disease. With our extensive expertise in genetic engineering and cell line development, our company delivers high-quality CANT1 Gene Knockout Cell Lines that empower scientific progress in both basic research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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