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CALML4 Knockout Cell Lines

Gene: CALML4

Official Full Name: calmodulin like 4provided by HGNC

Gene Summary: Enables myosin head/neck binding activity. Involved in brush border assembly. Located in microvillus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08997 CALML4 Knockout cell line (HeLa) Human CALML4 1:3~1:6 Negative Online Inquiry
KO08998 CALML4 Knockout cell line (HCT 116) Human CALML4 1:2~1:4 Negative Online Inquiry
KO08999 CALML4 Knockout cell line (HEK293) Human CALML4 1:3~1:6 Negative Online Inquiry
KO09000 CALML4 Knockout cell line (A549) Human CALML4 1:3~1:4 Negative Online Inquiry

Background

CALML4 Gene Knockout Cell Lines are an innovative biological research tool designed to facilitate the study of the CALML4 gene, which encodes a calcium-binding protein involved in various cellular processes, including cell signaling and proliferation. By generating specific knockout variants of this gene, these cell lines provide researchers with the ability to probe the functional role of CALML4 in cellular contexts, paving the way for deeper insights into its implications in disease mechanisms, especially in cancer and cardiac disorders.

The primary mechanism of action is based on the targeted disruption of the CALML4 gene through CRISPR/Cas9 technology or other gene-editing methodologies. This results in a loss-of-function phenotype, allowing scientists to observe differences in cellular behavior compared to wild-type cell lines. Researchers can utilize these cell lines to assess fundamental biological processes, drug responses, and potential therapeutic strategies—ultimately translating findings into potential clinical applications.

The scientific importance of CALML4 Gene Knockout Cell Lines lies in their broad utility in both basic and applied research settings. They are essential for elucidating the molecular pathways involving CALML4, which can lead to significant advancements in understanding oncogenic processes and heart-related conditions. Compared to alternative models, such as overexpression systems or non-specific siRNA silencing, these knockout lines provide a more precise and stable platform for interrogating gene function.

For researchers and clinicians, the value of CALML4 Gene Knockout Cell Lines is amplified by their potential for novel discovery and therapeutic insights. By enabling rigorous study of gene function and downstream effects, these cell lines can facilitate the development of targeted therapies that could improve patient outcomes.

With a commitment to advancing scientific research, our company specializes in high-quality biological products, employing cutting-edge technology to ensure that researchers have access to reliable models that support their groundbreaking scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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