Gene: C8G
Official Full Name: complement C8 gamma chainprovided by HGNC
Gene Summary: The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity. [provided by RefSeq, Jul 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38753 | C8G Knockout cell line (HeLa) | Human | C8G | 1:3~1:6 | Negative | Online Inquiry |
KO38754 | C8G Knockout cell line (A549) | Human | C8G | 1:3~1:4 | Negative | Online Inquiry |
C8G Gene Knockout Cell Lines are a specialized suite of genetically modified cell lines designed to facilitate the detailed study of gene function and the role of specific genetic sequences in cellular processes. These cell lines are derived from well-characterized human or animal sources and specifically engineered to exhibit a complete ablation of the C8G gene. The meticulous knockout process is achieved through advanced technologies such as CRISPR/Cas9 or homologous recombination, ensuring precise editing and functional verification.
The primary function of C8G Gene Knockout Cell Lines is to serve as invaluable tools for researchers investigating the molecular mechanisms that govern various biological pathways influenced by the C8G gene. By eliminating this specific gene, scientists can explore the downstream effects on gene expression, cellular behavior, and metabolic functions, providing critical insights into biological processes such as signal transduction, immune response, or disease manifestation.
In clinical and research settings, these cell lines hold significant scientific importance. They can be employed in drug discovery and development, helping to identify new therapeutic targets while facilitating biomarker discovery for various diseases, including cancer and genetic disorders. Furthermore, the understanding gained from these models can guide the design of gene therapies or other innovative treatment modalities.
What sets C8G Gene Knockout Cell Lines apart from alternative models is their high specificity and reliability. Unlike traditional methods that may provide inconsistent results or only partial knockouts, our meticulously validated cell lines guarantee the complete and reproducible ablation of the target gene. This allows for high-fidelity experimentation, giving researchers the confidence they need to derive meaningful conclusions.
Researchers and clinicians will find tremendous value in C8G Gene Knockout Cell Lines due to their versatility and applicability across various biological fields, including molecular biology, pharmacology, and translational medicine. Utilizing these cell lines can streamline research processes and enhance the efficiency of experimental designs, ultimately leading to faster discoveries and innovations.
At [Company Name], we pride ourselves on our commitment to advancing scientific research through high-quality biological products. Our expertise in genetic engineering and a robust portfolio of gene knockout models equip researchers with the tools they need to make significant strides in understanding complex biological systems.
Please note that all services are for research use only. Not intended for any clinical use.
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