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BRD3 Knockout Cell Lines

Gene: BRD3

Official Full Name: bromodomain containing 3provided by HGNC

Gene Summary: This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34345 BRD3 Knockout cell line (HeLa) Human BRD3 1:3~1:6 Negative Online Inquiry
KO34346 BRD3 Knockout cell line (HCT 116) Human BRD3 1:2~1:4 Negative Online Inquiry
KO34347 BRD3 Knockout cell line (HEK293) Human BRD3 1:3~1:6 Negative Online Inquiry
KO34348 BRD3 Knockout cell line (A549) Human BRD3 1:3~1:4 Negative Online Inquiry

Background

BRD3 Gene Knockout Cell Lines represent a revolutionary advancement in the field of molecular biology and genetic research. These cell lines have been meticulously engineered to create a targeted deletion of the BRD3 gene, a member of the bromodomain and extraterminal (BET) family, which plays a pivotal role in regulating gene expression and influencing various cellular processes such as proliferation, differentiation, and apoptosis.

At the core of these knockout cell lines is the CRISPR-Cas9 technology, which enables precise genomic modifications. By effectively disrupting the BRD3 gene, researchers can elucidate its functional role in various biological contexts, particularly in cancer biology and inflammatory diseases. The mechanisms leading to altered cellular behavior, including changes in transcriptional regulation and chromatin remodeling, can be studied in a controlled environment, facilitating insights into disease mechanisms and potential therapeutic targets.

The scientific importance of BRD3 Gene Knockout Cell Lines extends across multiple research and clinical applications. Their utility in deciphering the oncogenic pathways driven by BRD3, coupled with their use in drug discovery efforts targeting BET proteins, underscore their significance. These cell lines enable researchers to model disease states more accurately and evaluate novel therapeutic agents, making them invaluable tools in both academic and pharmaceutical settings.

What sets these cell lines apart from alternatives is their high specificity and efficiency, ensuring reliable experimental outcomes. Additionally, they come with comprehensive documentation supporting optimal usage, minimizing variability in research outcomes. The ability to generate consistent and reproducible data is crucial for researchers aiming to draw meaningful conclusions from their experiments.

The value of BRD3 Gene Knockout Cell Lines to researchers and clinicians cannot be overstated. By facilitating groundbreaking discoveries and potential therapies, they serve as a catalyst for advancement in personalized medicine and precision therapeutics.

With a commitment to quality and innovation, our company specializes in providing top-tier genetic tools and resources, aiming to empower scientists in their pursuit of scientific excellence. Our expertise in gene editing technologies ensures that every product we offer, including the BRD3 Gene Knockout Cell Lines, is of the highest standard, designed to meet the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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