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BPNT2 Knockout Cell Lines

Gene: BPNT2

Official Full Name: 3'(2'), 5'-bisphosphate nucleotidase 2provided by HGNC

Gene Summary: This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. [provided by RefSeq, Dec 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07788 BPNT2 Knockout cell line (HeLa) Human BPNT2 1:3~1:6 Negative Online Inquiry
KO07789 BPNT2 Knockout cell line (HCT 116) Human BPNT2 1:2~1:4 Negative Online Inquiry
KO07790 BPNT2 Knockout cell line (HEK293) Human BPNT2 1:3~1:6 Negative Online Inquiry
KO07791 BPNT2 Knockout cell line (A549) Human BPNT2 1:3~1:4 Negative Online Inquiry

Background

BPNT2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the BPNT2 gene, which encodes a crucial enzyme involved in cellular metabolism and nucleotide salvage pathways. These knockout models facilitate in-depth studies into the gene's functional roles, providing valuable insights into biochemical processes and cellular behaviors that are influenced by BPNT2 activity.

The key function of BPNT2 involves the hydrolysis of phosphonates, playing a critical role in nucleotide metabolism within cells. By disrupting the expression of this gene, researchers can dissect the metabolic alterations and biological consequences that arise due to the deficiency of this enzymatic activity. These insights are vital for understanding various physiological and pathological conditions, including metabolic disorders and cancer, where cell metabolism is often dysregulated.

From a scientific perspective, BPNT2 Gene Knockout Cell Lines are invaluable tools for researchers aiming to elucidate the gene's role in cellular physiology and its potential as a therapeutic target. In clinical settings, these models can pave the way for the development of innovative treatment strategies, particularly in diseases linked to metabolic dysfunction.

What sets BPNT2 Gene Knockout Cell Lines apart from traditional cell line models is their precise gene-editing design, ensuring a complete knockout of BPNT2. This specificity reduces confounding factors that may arise from incomplete gene disruption, enhancing the reliability of experimental results.

Incorporating BPNT2 Gene Knockout Cell Lines into research enables scientists to generate more accurate data, driving advancements in our understanding of metabolic processes and aiding the development of novel therapeutic approaches. For researchers and clinicians focused on metabolic research and drug development, these knockout cell lines represent a crucial resource.

Our company specializes in providing expertly engineered biological products that support cutting-edge research. With a commitment to scientific excellence, we deliver high-quality cell line models tailored to meet the diverse needs of the scientific community, enabling groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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