Gene: BCAS1
Official Full Name: brain enriched myelin associated protein 1provided by HGNC
Gene Summary: This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Apr 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34085 | BCAS1 Knockout cell line (A549) | Human | BCAS1 | 1:3~1:4 | Negative | Online Inquiry |
BCAS1 Gene Knockout Cell Lines are genetically modified cell lines that specifically lack the expression of the BCAS1 gene, which is known to be implicated in various biological processes and disease mechanisms, particularly in breast cancer development and progression. These cell lines are designed to be used as powerful tools for researchers aiming to elucidate the role of the BCAS1 gene in cellular functions and its contributions to oncogenic pathways.
The primary function of BCAS1 Gene Knockout Cell Lines is to facilitate the study of gene function through the examination of phenotypic changes that occur in the absence of the BCAS1 gene. By utilizing CRISPR/Cas9 and other gene-editing technologies, these cell lines provide a precise means to observe the effects of BCAS1 loss on cellular behaviors such as proliferation, migration, and response to therapeutic agents. Researchers can employ these models to uncover molecular interactions and signaling pathways influenced by BCAS1, enhancing our understanding of its contributions to cancer biology.
The scientific relevance of BCAS1 Gene Knockout Cell Lines extends into both fundamental and applied research, making them invaluable in clinical translational studies. They can aid in the development of novel therapeutic strategies targeting breast cancer and other related diseases. In addition, these cell lines serve as a reliable platform for drug testing, offering insights into the efficacy of BCAS1-targeted therapies and enabling researchers to identify biomarkers that can predict treatment responses.
One of the distinct advantages of our BCAS1 Gene Knockout Cell Lines is their high specificity and reproducibility compared to traditional knockdown methods, which can lead to incomplete gene silencing or off-target effects. Additionally, these knockout models provide an ideal basis for downstream applications, including high-throughput screening and functional assays, which are essential for accelerating our understanding of gene functions in pathology.
By investing in BCAS1 Gene Knockout Cell Lines, researchers, and clinicians can gain access to cutting-edge cell models that significantly enhance experimental precision and reliability. Our company specializes in providing high-quality, tailored genetic tools for the scientific community, leveraging our expertise in molecular biology and genetic engineering to support innovative research initiatives.
Please note that all services are for research use only. Not intended for any clinical use.
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