Gene: BATF3
Official Full Name: basic leucine zipper ATF-like transcription factor 3provided by HGNC
Gene Summary: This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19479 | BATF3 Knockout cell line (HeLa) | Human | BATF3 | 1:3~1:6 | Negative | Online Inquiry |
KO19480 | BATF3 Knockout cell line (HCT 116) | Human | BATF3 | 1:2~1:4 | Negative | Online Inquiry |
KO19481 | BATF3 Knockout cell line (HEK293) | Human | BATF3 | 1:3~1:6 | Negative | Online Inquiry |
KO19482 | BATF3 Knockout cell line (A549) | Human | BATF3 | 1:3~1:4 | Negative | Online Inquiry |
BATF3 Gene Knockout Cell Lines are genetically engineered models that facilitate the study of the basic immunological processes by creating targeted disruptions in the BATF3 gene. This gene is crucial for the development and function of various immune cell subsets, particularly in the differentiation of dendritic cells, which play a pivotal role in antigen presentation and activation of T cells. The BATF3 Gene Knockout Cell Lines serve as invaluable tools for researchers investigating the complexities of immune response and the underlying mechanisms of immune-related diseases, including cancer and autoimmune disorders.
These specialized cell lines function through the complete ablation of BATF3 expression, leading to altered signaling pathways and resulting in the downregulation of dendritic cell maturation and function. By utilizing these knockout cell lines, scientists can delve into the immunological ramifications of BATF3 loss, enabling them to elucidate its role in immune system regulation and response to therapies.
The scientific importance of BATF3 Gene Knockout Cell Lines extends to both research and clinical applications, including vaccine development and personalized medicine strategies. These models allow for the experimental manipulation of immune responses, providing insights that can lead to novel therapeutic approaches.
What sets our BATF3 Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility, which are critical for gaining reliable and interpretable data in immunology research. Furthermore, these cell lines are subjected to rigorous quality control measures, ensuring optimal performance and consistency across experiments.
By incorporating BATF3 Gene Knockout Cell Lines into your research toolkit, you gain a powerful asset that enhances the ability to dissect immune mechanisms and explore innovative therapeutic avenues. Our commitment to advancing the field of immunology is backed by years of experience in developing high-quality biological products tailored for the scientific community. Together, we can foster groundbreaking discoveries in immune cell biology and beyond.
Please note that all services are for research use only. Not intended for any clinical use.
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