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BATF2 Knockout Cell Lines

Gene: BATF2

Official Full Name: basic leucine zipper ATF-like transcription factor 2provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in defense response to protozoan; myeloid dendritic cell differentiation; and regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00873 BATF2 Knockout cell line(293T) Human BATF2 1:3~1:6 Negative Online Inquiry
KO19483 BATF2 Knockout cell line (HCT 116) Human BATF2 1:2~1:4 Negative Online Inquiry

Background

BATF2 Gene Knockout Cell Lines represent a powerful tool for researchers investigating the role of the BATF2 gene in various biological processes, including immune responses and inflammation. These specialized cell lines have been genetically modified to disrupt the normal expression of the BATF2 gene, allowing for the detailed study of its functions and interactions in cellular pathways. By providing a model in which the effects of BATF2 deficiency can be assessed, these knockout cell lines enable researchers to elucidate the gene's contributions to disease mechanisms, thus advancing our understanding of both basic and applied biological sciences.

Mechanistically, BATF2 knockouts are created via CRISPR/Cas9 technology, which allows for precise editing of the genome and promotes targeted gene disruption. As a transcription factor, BATF2 is implicated in the regulation of genes involved in the immune system, particularly within T cells and macrophages. Utilizing these cell lines, scientists can examine how the absence of BATF2 affects cell proliferation, differentiation, and response to stimuli, offering critical insights into its role in health and disease.

In research settings, BATF2 Gene Knockout Cell Lines play a significant role in deciphering complex immunological behaviors and their implications for autoimmune diseases and cancer therapies. Clinically, the potential to develop therapies that target or mimic the BATF2 pathway can lead to novel treatment strategies, offering significant implications for patient care.

What sets BATF2 knockouts apart from other gene editing approaches is their high specificity, reliability, and reproducibility. The absence of off-target effects, often associated with traditional methods, further enhances the credibility of findings derived from these lines. Researchers will appreciate the user-friendly protocols and thorough validation provided by our team, ensuring a seamless integration of these cell lines into ongoing experiments.

Our company prides itself on being at the forefront of biological products, combining cutting-edge technology with a commitment to quality and integrity. We empower researchers and clinicians with innovative tools to deepen their understanding of genetic functions and improve therapeutic outcomes, exemplified by our BATF2 Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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