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BASP1 Knockout Cell Lines

Gene: BASP1

Official Full Name: brain abundant membrane attached signal protein 1provided by HGNC

Gene Summary: This gene encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31909 BASP1 Knockout cell line (HeLa) Human BASP1 1:3~1:6 Negative Online Inquiry
KO31910 BASP1 Knockout cell line (HEK293) Human BASP1 1:3~1:6 Negative Online Inquiry
KO31911 BASP1 Knockout cell line (A549) Human BASP1 1:3~1:4 Negative Online Inquiry

Background

BASP1 Gene Knockout Cell Lines are biologically engineered cell lines that have been specifically created to eliminate the endogenous expression of the BASP1 gene, a gene associated with cellular signaling processes and membrane dynamics. These knockout cell lines serve as powerful tools for researchers aiming to study the role of BASP1 in various biological contexts, including cell stress responses, neuronal activities, and cancer biology.

The key function of BASP1 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for investigating the phenotypic consequences of the loss of BASP1. By employing CRISPR/Cas9 gene-editing technology, these cell lines display a precise and efficient silencing of the BASP1 gene, allowing researchers to elucidate the gene’s role in processes such as synaptic transmission and tissue regeneration. As a research model, these knockout cell lines enable scientists to observe changes in cellular behavior, gene expression profiles, and signaling pathways, shedding light on the complex mechanisms governing cellular functions.

The scientific importance of BASP1 Gene Knockout Cell Lines spans various research and clinical applications. They are particularly valuable in the study of neurological disorders, where deregulation of BASP1 has been implicated. Furthermore, these cell lines are essential for drug discovery efforts aimed at targeting signaling pathways associated with cancer, making them a pivotal resource in translational medicine.

Compared to traditional cell lines, BASP1 Gene Knockout Cell Lines offer enhanced specificity and reduced variability in experimental outcomes, thus improving the reliability of experimental data. Compared to other genetic modification techniques, the precision of CRISPR/Cas9 allows for reproducible knockouts without off-target effects, making these cell lines superior for in-depth functional studies.

Researchers and clinicians will find great value in utilizing BASP1 Gene Knockout Cell Lines due to the essential insights they provide into the role of BASP1 in health and disease. The capability to manipulate this gene within a cellular context allows for the exploration of innovative therapeutic approaches that may lead to significant advancements in patient care.

As experts in cellular biology products, we pride ourselves on delivering high-quality and rigorously validated models. Our commitment to supporting scientific progress ensures that BASP1 Gene Knockout Cell Lines represent not only a state-of-the-art research tool but also a step towards unlocking new therapeutic possibilities.

Please note that all services are for research use only. Not intended for any clinical use.

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