Gene: ASPRV1
Official Full Name: aspartic peptidase retroviral like 1provided by HGNC
Gene Summary: Filaggrin is a structural protein that is crucial for in the development and maintenance of the skin barrier. This gene encodes a retroviral-like protease involved in profilaggrin-to-filaggrin processing. Expression is found primarily in the epidermis and inner root sheath of hair follicles. [provided by RefSeq, May 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21954 | ASPRV1 Knockout cell line (HEK293) | Human | ASPRV1 | 1:3~1:6 | Negative | Online Inquiry |
ASPRV1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to target and disrupt the expression of the ASPRV1 gene. Utilizing CRISPR-Cas9 technology, these cell lines enable researchers to study the functional roles of the ASPRV1 gene in various biological processes and disease states. By creating null mutations, the ASPRV1 Gene Knockout Cell Lines facilitate the analysis of phenotypic changes associated with the loss of gene function, enabling insights into gene regulation, cellular metabolism, and signaling pathways.
The key function of these knockout cell lines is their contribution to understanding the implications of the ASPRV1 gene in health and disease. ASPRV1 is implicated in several cellular mechanisms, including stress response, autophagy, and apoptosis, making the study of this gene relevant to research areas such as cancer, neurodegeneration, and metabolic disorders. The ability to manipulate this gene effectively allows for the exploration of its role in cellular homeostasis and disease progression, offering a unique tool for investigators focused on gene function and therapeutic target validation.
One of the significant advantages of our ASPRV1 Gene Knockout Cell Lines is the enhanced specificity and efficiency provided by CRISPR technology, compared to traditional methods such as homologous recombination. Moreover, these cell lines come with validated off-target profiles, ensuring that experimental results are both reliable and reproducible. This specificity minimizes the potential for confounding results, providing researchers with high-quality data that supports robust scientific conclusions.
The value of ASPRV1 Gene Knockout Cell Lines extends beyond basic research; they hold considerable promise for translational applications in precision medicine. By identifying the role of the ASPRV1 gene in specific disease contexts, clinicians may develop gene-targeted therapies or diagnostics that pave the way for improved patient outcomes.
Our company is committed to advancing research through innovative biotechnology solutions. With a strong background in genetic engineering and a focus on quality control, our products are designed to empower scientists and clinicians alike, ensuring that you have access to the most reliable tools for your research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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