Gene: ADGRV1
Official Full Name: adhesion G protein-coupled receptor V1provided by HGNC
Gene Summary: This gene encodes a member of the G-protein coupled receptor superfamily. The encoded protein contains a 7-transmembrane receptor domain, binds calcium and is expressed in the central nervous system. Mutations in this gene are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25250 | ADGRV1 Knockout cell line (HCT 116) | Human | ADGRV1 | 1:2~1:4 | Negative | Online Inquiry |
KO25251 | ADGRV1 Knockout cell line (HEK293) | Human | ADGRV1 | 1:3~1:6 | Negative | Online Inquiry |
KO25252 | ADGRV1 Knockout cell line (A549) | Human | ADGRV1 | 1:3~1:4 | Negative | Online Inquiry |
ADGRV1 Gene Knockout Cell Lines are specialized biological products designed to facilitate the study of the ADGRV1 gene, which encodes for a protein implicated in various physiological and pathological processes, including cell signaling and membrane dynamics. These knockout cell lines enable researchers to precisely examine the consequences of ADGRV1 absence, thereby elucidating its role in cellular functions and disease mechanisms.
The creation of these knockout cell lines employs advanced CRISPR/Cas9 gene-editing technology, ensuring that the ADGRV1 gene is inactivated with high specificity and efficiency. This results in a cellular model that exhibits altered signaling pathways, providing vital insights into how ADGRV1 contributes to both normal and dysregulated cellular behaviors. Researchers can leverage these cell lines to explore a myriad of scientific questions, from developmental biology to cancer research, making them invaluable tools in the quest to understand complex biological systems.
The scientific significance of ADGRV1 Gene Knockout Cell Lines is underscored by their applications in both basic research and clinical studies, including drug discovery and mechanistic studies of various diseases. Their ability to simulate a gene knockdown condition offers a more accurate representation of pathophysiological states in vitro, as opposed to traditional methods that may lack specificity.
Compared to other genetic manipulation techniques, these knockout cell lines provide a straightforward, reliable means of studying the functional outcomes of gene loss, minimizing off-target effects. This focused approach enhances data clarity and reproducibility, setting them apart from non-specific methodologies.
Researchers and clinicians recognize the profound implications of these cell lines in accelerating the understanding of gene function and offering insights that could lead to novel therapeutic strategies. By providing a definitive means to investigate gene activity and its role in disease, the ADGRV1 Gene Knockout Cell Lines represent an essential addition to any laboratory's toolkit.
With extensive experience in cellular biology and genetic engineering, our company is committed to offering high-quality, reliable products that support cutting-edge research and innovation. Our dedication to scientific excellence ensures that ADGRV1 Gene Knockout Cell Lines and our other offerings empower researchers to drive discovery in their fields.
Please note that all services are for research use only. Not intended for any clinical use.
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