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ABHD17B Knockout Cell Lines

Gene: ABHD17B

Official Full Name: abhydrolase domain containing 17B, depalmitoylaseprovided by HGNC

Gene Summary: Enables palmitoyl-(protein) hydrolase activity. Involved in protein depalmitoylation. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23037 ABHD17B Knockout cell line (HeLa) Human ABHD17B 1:3~1:6 Negative Online Inquiry
KO23038 ABHD17B Knockout cell line (HCT 116) Human ABHD17B 1:2~1:4 Negative Online Inquiry
KO23039 ABHD17B Knockout cell line (HEK293) Human ABHD17B 1:3~1:6 Negative Online Inquiry
KO23040 ABHD17B Knockout cell line (A549) Human ABHD17B 1:3~1:4 Negative Online Inquiry

Background

ABHD17B Gene Knockout Cell Lines are precision-engineered cellular models crucial for studying the biological functions of the ABHD17B gene, a member of the serine hydrolase family implicated in various physiological processes, including lipid metabolism and neurotransmission. These knockout cell lines are generated using CRISPR-Cas9 technology, which facilitates the precise deletion of the ABHD17B gene, allowing researchers to investigate its role in cellular pathways and disease mechanisms.

The key functions of ABHD17B involve the hydrolysis of fatty acid amides and other lipid mediators, making these cell lines pivotal for studies focusing on lipid signaling and its ramifications in metabolic disorders or neurodegenerative diseases. By employing these knockout models, scientists can elucidate the specific contributions of ABHD17B to cellular behavior, providing profound insights into its potential as a therapeutic target.

In terms of scientific importance, these cell lines are vital for advancing research in pharmacology and toxicology, allowing for the assessment of drug candidates and their interactions with lipid metabolism pathways. Clinically, an understanding of the ABHD17B gene’s role could pave the way for innovative treatments targeting conditions such as obesity, anxiety, and pain modulation.

Compared to traditional gene silencing methods, our ABHD17B Gene Knockout Cell Lines offer several advantages, including durability, specificity, and reproducibility. These models eliminate off-target effects often associated with RNA interference, enabling more reliable results. Researchers will appreciate the ease of use and immediate applicability in high-throughput screening assays and mechanistic studies.

For scientists and clinicians seeking to deepen their understanding of lipid-related pathophysiology, our ABHD17B Gene Knockout Cell Lines stand as a valuable resource, facilitating significant advancements in both fundamental and translational research. Our commitment to quality and innovation in biological products ensures that you are accessing cell lines that meet the highest standards of scientific rigor, empowering your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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