SMARCA4 Knockout cell line (HCT 116)

Catalog Number: KO13961

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Specifications

Product Information
Product Name	SMARCA4 Knockout cell line (HCT 116)
specification	1*10^6
Storage and transportation	Dry ice preservation/T25 live cell transportation.
Cell morphology	Epithelioid, adherent cell
Passage ratio	1:2~1:4
species	Human
Gene	SMARCA4
Gene ID	6597
Build method	Electric rotation method / virus method
Mycoplasma testing	Negative
Cultivation system	90%McCOYs 5A+10% FBS
Parental Cell Line	HCT 116
Quality Control	Genotype: SMARCA4 Knockout cell line (HCT 116) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4provided by HGNC
Also known as	BRG1; CSS4; SNF2; SWI2; MRD16; RTPS2; BAF190; OTSC12; SNF2L4; SNF2LB; hSNF2b; BAF190A; SNF2-beta
Gene Description	The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Expression	Ubiquitous expression in testis (RPKM 21.8), brain (RPKM 14.5) and 25 other tissues See more

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