PPP3CB Knockout cell line (HeLa)

Catalog Number: KO10549

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Specifications

Product Information
Product Name	PPP3CB Knockout cell line (HeLa)
specification	1*10^6
Storage and transportation	Dry ice preservation/T25 live cell transportation.
Cell morphology	Epithelioid, adherent cell
Passage ratio	1:3~1:6
species	Human
Gene	PPP3CB
Gene ID	5532
Build method	Electric rotation method / virus method
Mycoplasma testing	Negative
Cultivation system	90%DMEM+10% FBS
Parental Cell Line	HeLa
Quality Control	Genotype: PPP3CB Knockout cell line (HeLa) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	protein phosphatase 3 catalytic subunit betaprovided by HGNC
Also known as	CNA2; CALNB; CALNA2; PP2Bbeta
Gene Description	Enables several functions, including calmodulin binding activity; calmodulin-dependent protein phosphatase activity; and protein phosphatase 2B binding activity. Involved in several processes, including calcineurin-NFAT signaling cascade; positive regulation of lysosome organization; and positive regulation of protein localization to nucleus. Located in cytoplasm. Part of calcineurin complex. Implicated in aortic valve stenosis. Biomarker of focal segmental glomerulosclerosis and schizophrenia. [provided by Alliance of Genome Resources, Apr 2025]
Expression	Ubiquitous expression in brain (RPKM 40.2), fat (RPKM 17.4) and 24 other tissues See more

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