OAS1 Knockout cell line (AC16)

Name: OAS1 Knockout cell line (AC16)
Brand: CD Biosynsis
SKU: KOA14515
Availability: InStock

Catalog Number: KOA14515

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Specifications

Product Information
Product Name	OAS1 Knockout cell line (AC16)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Fibroblast-like, adherent
Passage ratio	1：3-1：4
species	Human
Gene	OAS1
Gene ID	4938
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM/F12+10% FBS
Parental Cell Line	AC16
Quality Control	Genotype: OAS1 Knockout cell line (AC16)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	2'-5'-oligoadenylate synthetase 1provided by HGNC
Also known as	OIAS; IFI-4; OIASI; IMD100; E18/E16
Gene Description	This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cellular processes like cell growth and apoptosis. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection, including SARS-CoV-2, and diabetes mellitus, type 1. This gene is located in a cluster of related genes on chromosome 12. [provided by RefSeq, May 2022]
Expression	Ubiquitous expression in spleen (RPKM 18.0), colon (RPKM 15.8) and 24 other tissues See more

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