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NR1H4 Knockout cell line (BEAS-2B)

Catalog Number: KOA27286

Price: Online Inquiry

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Specifications

Product Information
Product Name NR1H4 Knockout cell line (BEAS-2B)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adherent
Passage ratio 1:3~1:4
species Human
Gene NR1H4
Gene ID 9971
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90% DMEM+10% FBS
Parental Cell Line BEAS-2B
Quality Control Genotype: NR1H4 Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name nuclear receptor subfamily 1 group H member 4provided by HGNC
Also known as BAR; FXR; HRR1; HRR-1; PFIC5; RIP14
Gene Description This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]
Expression Biased expression in liver (RPKM 14.7), small intestine (RPKM 8.3) and 6 other tissues See more

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