MGAT5 Knockout cell line (NCM460)

Catalog Number: KOA76514

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Specifications

Product Information
Product Name	MGAT5 Knockout cell line (NCM460)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adheren
Passage ratio	1:2~1:3
species	Human
Gene	MGAT5
Gene ID	4249
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%RPMI-1640+10%FBS
Parental Cell Line	NCM460
Quality Control	Genotype: MGAT5 Knockout cell line (NCM460)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferaseprovided by HGNC
Also known as	GNT-V; GNT-VA; MGAT5A; glcNAc-T V
Gene Description	The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011]
Expression	Ubiquitous expression in heart (RPKM 14.6), lymph node (RPKM 12.4) and 24 other tissues See more

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