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GALC Knockout cell line (AC16)

Catalog Number: KOA15803

Price: Online Inquiry

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Specifications

Product Information
Product Name GALC Knockout cell line (AC16)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Fibroblast-like, adherent
Passage ratio 1:3-1:4
species Human
Gene GALC
Gene ID 2581
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90% DMEM/F12+10% FBS
Parental Cell Line AC16
Quality Control Genotype: GALC Knockout cell line (AC16)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name galactosylceramidaseprovided by HGNC
Gene Description This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Expression Ubiquitous expression in small intestine (RPKM 14.9), duodenum (RPKM 14.2) and 25 other tissues See more

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