FTO Knockout cell line (HCT 116)

Catalog Number: KO09254

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Specifications

Product Information
Product Name	FTO Knockout cell line (HCT 116)
specification	1*10^6
Storage and transportation	Dry ice preservation/T25 live cell transportation.
Cell morphology	Epithelioid, adherent cell
Passage ratio	1:2~1:4
species	Human
Gene	FTO
Gene ID	79068
Build method	Electric rotation method / virus method
Mycoplasma testing	Negative
Cultivation system	90%McCOYs 5A+10% FBS
Parental Cell Line	HCT 116
Quality Control	Genotype: FTO Knockout cell line (HCT 116) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	FTO alpha-ketoglutarate dependent dioxygenaseprovided by HGNC
Also known as	GDFD; IFEX9; ALKBH9; BMIQ14
Gene Description	This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Expression	Ubiquitous expression in brain (RPKM 7.3), adrenal (RPKM 4.2) and 25 other tissues See more

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