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CLTRN Knockout cell line (A549)

Catalog Number: KO18660

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Specifications

Product Information
Product Name CLTRN Knockout cell line (A549)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:3~1:4
species Human
Gene CLTRN
Gene ID 57393
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90% F12K+10% FBS
Parental Cell Line A549
Quality Control Genotype: CLTRN Knockout cell line (A549) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name collectrin, amino acid transport regulatorprovided by HGNC
Also known as NX17; NX-17; TMEM27
Gene Description This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]
Expression Biased expression in kidney (RPKM 116.5) and liver (RPKM 8.9) See more

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