AGA Knockout cell line (U-2932)

Catalog Number: KOA47986

Specifications Downloads Related products

Specifications

Product Information
Product Name	AGA Knockout cell line (U-2932)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Human Lymphocyte-like, suspension
Passage ratio	1：2-1：4
species	Human
Gene	AGA
Gene ID	175
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%RPMI-1640+10%FBS
Parental Cell Line	U-2932
Quality Control	Genotype: AGA Knockout cell line (U-2932)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	aspartylglucosaminidaseprovided by HGNC
Also known as	GA; AGU; ASRG
Gene Description	This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. This enzyme is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. Mutations in this gene are associated with the lysosomal storage disease aspartylglycosaminuria that results in progressive neurodegeneration. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is subject to proteolytic processing. [provided by RefSeq, Nov 2015]
Expression	Ubiquitous expression in thyroid (RPKM 10.5), testis (RPKM 10.0) and 25 other tissues See more

Downloads

Datasheet

You may be interested in:

Please note that all services are for research use only. Not intended for any clinical use.

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.