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TRIB3 Knockout cell line (U-2932)

Catalog Number: KOA38792

Price: Online Inquiry

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Specifications

Product Information
Product Name TRIB3 Knockout cell line (U-2932)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Human Lymphocyte-like, suspension
Passage ratio 1:2-1:4
species Human
Gene TRIB3
Gene ID 57761
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%RPMI-1640+10%FBS
Parental Cell Line U-2932
Quality Control Genotype: TRIB3 Knockout cell line (U-2932)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name tribbles pseudokinase 3provided by HGNC
Also known as NIPK; SINK; TRB3; SKIP3; C20orf97
Gene Description The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]
Expression Broad expression in thyroid (RPKM 19.9), liver (RPKM 5.0) and 16 other tissues See more

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