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SCRIB Knockout cell line (HCT 116)

Catalog Number: KO08551

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Specifications

Product Information
Product Name SCRIB Knockout cell line (HCT 116)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:2~1:4
species Human
Gene SCRIB
Gene ID 23513
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90%McCOYs 5A+10% FBS
Parental Cell Line HCT 116
Quality Control Genotype: SCRIB Knockout cell line (HCT 116) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name scribble planar cell polarity proteinprovided by HGNC
Also known as CRIB1; SCRB1; SCRIB1; Vartul; oSCRIB
Gene Description This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Expression Ubiquitous expression in colon (RPKM 9.3), skin (RPKM 9.0) and 25 other tissues See more

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