Home / SCRIB Knockout Cell Lines

SCRIB Knockout Cell Lines

Gene: SCRIB

Official Full Name: scribble planar cell polarity proteinprovided by HGNC

Gene Summary: This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08550 SCRIB Knockout cell line (HeLa) Human SCRIB 1:3~1:6 Negative Online Inquiry
KO08551 SCRIB Knockout cell line (HCT 116) Human SCRIB 1:2~1:4 Negative Online Inquiry
KO08552 SCRIB Knockout cell line (HEK293) Human SCRIB 1:3~1:6 Negative Online Inquiry
KO08553 SCRIB Knockout cell line (A549) Human SCRIB 1:3~1:4 Negative Online Inquiry

Background

SCRIB Gene Knockout Cell Lines represent a groundbreaking advancement in the field of gene editing and functional genomics. These cell lines are specifically engineered to possess targeted disruptions in the SCRIB gene, known for its pivotal role in cellular signaling, polarity, and development. By employing cutting-edge CRISPR-Cas9 technology, SCRIB Gene Knockout Cell Lines allow researchers to elucidate the intricate functions of SCRIB in various biological contexts, enabling a deeper understanding of its contributions to cell adhesion, migration, and proliferation.

The key function of SCRIB Gene Knockout Cell Lines lies in their ability to serve as a robust platform for studying SCRIB-related pathways and their implications in health and disease. The knockout of the SCRIB gene leads to altered cellular dynamics, which researchers can investigate to uncover its role in cancer progression, tissue homeostasis, and stem cell differentiation. This unique mechanistic insight is of paramount importance in both basic and translational research settings, offering a pathway to novel therapeutic targets and biomarker development.

Compared to traditional wild-type cell lines or alternative knockout models, SCRIB Gene Knockout Cell Lines offer the advantage of precise, specific gene targeting coupled with reliable phenotypic outcomes. This specificity reduces off-target effects, increasing experimental reproducibility and the reliability of data produced from these models. Furthermore, they are designed for convenience, supporting a range of applications from high-throughput screening to functional assays, thereby enhancing overall laboratory efficiency.

For researchers and clinicians focused on oncology, developmental biology, or regenerative medicine, SCRIB Gene Knockout Cell Lines are invaluable tools that provide rigorous models to test hypotheses and pave the way for clinical innovations. By supplying these advanced cell lines, we empower the scientific community to accelerate discoveries that could lead to significant breakthroughs in therapeutic strategies.

Our company, with its expertise in gene editing technologies and a commitment to high-quality biological products, proudly offers SCRIB Gene Knockout Cell Lines as a testament to our dedication to fostering advancements in life science research.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.