SCNN1A Knockout cell line (A549)

Catalog Number: KO35491

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Specifications

Product Information
Product Name	SCNN1A Knockout cell line (A549)
specification	1*10^6
Storage and transportation	Dry ice preservation/T25 live cell transportation.
Cell morphology	Epithelioid, adherent cell
Passage ratio	1:3~1:4
species	Human
Gene	SCNN1A
Gene ID	6337
Build method	Electric rotation method / virus method
Mycoplasma testing	Negative
Cultivation system	90% F12K+10% FBS
Parental Cell Line	A549
Quality Control	Genotype: SCNN1A Knockout cell line (A549) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	sodium channel epithelial 1 subunit alphaprovided by HGNC
Also known as	BESC2; ENaCa; SCNEA; SCNN1; LIDLS3; PHA1B1; ENaCalpha
Gene Description	Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]
Expression	Broad expression in kidney (RPKM 50.6), colon (RPKM 38.2) and 15 other tissues See more

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