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RORA Knockout cell line (A549)

Catalog Number: KO06959

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Specifications

Product Information
Product Name RORA Knockout cell line (A549)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:3~1:4
species Human
Gene RORA
Gene ID 6095
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90% F12K+10% FBS
Parental Cell Line A549
Quality Control Genotype: RORA Knockout cell line (A549) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name RAR related orphan receptor Aprovided by HGNC
Also known as ROR1; ROR2; ROR3; RZRA; NR1F1; RORa1; IDDECA; RORalpha; RZR-ALPHA
Gene Description The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]
Expression Broad expression in skin (RPKM 15.9), adrenal (RPKM 10.1) and 21 other tissues See more

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