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OTUB1 Knockout cell line (BEAS-2B)

Catalog Number: KOA24075

Price: Online Inquiry

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Specifications

Product Information
Product Name OTUB1 Knockout cell line (BEAS-2B)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adherent
Passage ratio 1:3~1:4
species Human
Gene OTUB1
Gene ID 55611
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90% DMEM+10% FBS
Parental Cell Line BEAS-2B
Quality Control Genotype: OTUB1 Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name OTU deubiquitinase, ubiquitin aldehyde binding 1provided by HGNC
Also known as OTB1; OTU1; HSPC263
Gene Description The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Expression Ubiquitous expression in brain (RPKM 29.9), placenta (RPKM 22.0) and 25 other tissues See more

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