ITGAM Knockout cell line (MRC-5)

Catalog Number: KOA92313

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Specifications

Product Information
Product Name	ITGAM Knockout cell line (MRC-5)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Fibroblast-like, adherent
Passage ratio	1：2-1：3
species	Human
Gene	ITGAM
Gene ID	3684
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%DMEM+10%FBS
Parental Cell Line	MRC-5
Quality Control	Genotype: ITGAM Knockout cell line (MRC-5)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	integrin subunit alpha Mprovided by HGNC
Also known as	CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6
Gene Description	This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Expression	Biased expression in bone marrow (RPKM 72.3), appendix (RPKM 14.6) and 6 other tissues See more

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