Intracellular Protein Biotinylation

Temporal Precision

From 10-minute TurboID labeling to sub-minute APEX2 snapshots, capture dynamic protein interactions at the exact moment they occur.

• TurboID: 10-minute labeling
• APEX2: sub-minute resolution
• BioID: 18-24 hr for weak interactors

Spatial Resolution

10-20 nm labeling radius ensures only proteins in immediate proximity to your target are captured, providing high-fidelity interaction maps.

Actual labeling radius varies by enzyme system and experimental conditions.

• 10-20 nm labeling radius
• Subcellular targeting options
• Organelle-specific labeling

Native Context

Labeling occurs in living cells before lysis, preserving weak and transient interactions that don't survive traditional co-immunoprecipitation.

• Preserves native interactions
• Catches transient associations
• No cross-linking artifacts