GPT2 Knockout cell line (293T)

Name: GPT2 Knockout cell line (293T)
Brand: CD Biosynsis
SKU: KOA00189
Availability: InStock

Catalog Number: KOA00189

Price: Online Inquiry

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Specifications

Product Information
Product Name	GPT2 Knockout cell line (293T)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:3~1:6
species	Human
Gene	GPT2
Gene ID	84706
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM+10%FBS
Parental Cell Line	293T
Quality Control	Genotype: GPT2 Knockout cell line (293T)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	glutamic--pyruvic transaminase 2provided by HGNC
Also known as	ALT2; GPT 2; MRT49; NEDSPM
Gene Description	This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Expression	Broad expression in fat (RPKM 41.2), pancreas (RPKM 29.0) and 15 other tissues See more

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