FIG4 Knockout cell line (U-2932)

Catalog Number: KOA42780

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Specifications

Product Information
Product Name	FIG4 Knockout cell line (U-2932)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Human Lymphocyte-like, suspension
Passage ratio	1：2-1：4
species	Human
Gene	FIG4
Gene ID	9896
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%RPMI-1640+10%FBS
Parental Cell Line	U-2932
Quality Control	Genotype: FIG4 Knockout cell line (U-2932)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	FIG4 phosphoinositide 5-phosphataseprovided by HGNC
Also known as	BOP; YVS; BTOP; SAC3; ALS11; CMT4J; KIAA0274; dJ249I4.1
Gene Description	The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008]
Expression	Ubiquitous expression in brain (RPKM 6.2), lung (RPKM 4.8) and 25 other tissues See more

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