CYP2C8 Knockout cell line (U-2932)
Catalog Number: KOA47174
Price: Online Inquiry
Catalog Number: KOA47174
Price: Online Inquiry
| Product Information | |
|---|---|
| Product Name | CYP2C8 Knockout cell line (U-2932) |
| specification | 1*10^6 |
| Storage and transportation | Shipped on dry ice; Store in liquid nitrogen |
| Cell morphology | Human Lymphocyte-like, suspension |
| Passage ratio | 1:2-1:4 |
| species | Human |
| Gene | CYP2C8 |
| Gene ID | 1558 |
| Build method | Electroporation/Lentivirus |
| Mycoplasma testing | negative |
| Cultivation system | 90%RPMI-1640+10%FBS |
| Parental Cell Line | U-2932 |
| Quality Control | Genotype: CYP2C8 Knockout cell line (U-2932)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins. |
| Gene Information | |
|---|---|
| Gene Official Full Name | cytochrome P450 family 2 subfamily C member 8provided by HGNC |
| Also known as | CPC8; CYPIIC8; CYP2C8DM; MP-12/MP-20 |
| Gene Description | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
| Expression | Restricted expression toward liver (RPKM 350.3) See more |
Please note that all services are for research use only. Not intended for any clinical use.
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