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CYP26B1 Knockout cell line (TPC-1)

Catalog Number: KOA54649

Price: Online Inquiry

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Specifications

Product Information
Product Name CYP26B1 Knockout cell line (TPC-1)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adherent
Passage ratio 1:5-1:8
species Human
Gene CYP26B1
Gene ID 56603
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%DMEM+10%FBS
Parental Cell Line TPC-1
Quality Control Genotype: CYP26B1 Knockout cell line (TPC-1)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name cytochrome P450 family 26 subfamily B member 1provided by HGNC
Also known as RHFCA; CYP26A2; P450RAI2; P450RAI-2
Gene Description This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
Expression Broad expression in testis (RPKM 9.5), skin (RPKM 9.2) and 21 other tissues See more

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