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CUL4B Knockout cell line (AC16)

Catalog Number: KOA12790

Price: Online Inquiry

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Specifications

Product Information
Product Name CUL4B Knockout cell line (AC16)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Fibroblast-like, adherent
Passage ratio 1:3-1:4
species Human
Gene CUL4B
Gene ID 8450
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90% DMEM/F12+10% FBS
Parental Cell Line AC16
Quality Control Genotype: CUL4B Knockout cell line (AC16)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name cullin 4Bprovided by HGNC
Also known as SFM2; MRXSC; CUL-4B; MRXHF2; MRXS15
Gene Description This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Expression Ubiquitous expression in testis (RPKM 18.5), ovary (RPKM 14.3) and 25 other tissues See more

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