Gene: TRAFD1
Official Full Name: TRAF-type zinc finger domain containing 1provided by HGNC
Gene Summary: The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).[supplied by OMIM, Dec 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03290 | TRAFD1 Knockout cell line (HeLa) | Human | TRAFD1 | 1:3~1:6 | Negative | Online Inquiry |
KO03291 | TRAFD1 Knockout cell line (HCT 116) | Human | TRAFD1 | 1:2~1:4 | Negative | Online Inquiry |
KO03292 | TRAFD1 Knockout cell line (HEK293) | Human | TRAFD1 | 1:3~1:6 | Negative | Online Inquiry |
KO03293 | TRAFD1 Knockout cell line (A549) | Human | TRAFD1 | 1:3~1:4 | Negative | Online Inquiry |
TRAFD1 Gene Knockout Cell Lines are genetically modified cellular models where the TRAFD1 gene has been systematically disrupted, allowing for the study of this gene’s role in cellular processes and disease mechanisms. TRAFD1 serves as an important mediator of various signaling pathways, particularly those involved in immune responses and inflammation. By knocking out this gene, researchers can investigate its biological functions and how its impairment may lead to alterations in signaling cascades, ultimately influencing cell behavior, cytokine production, and immune cell activation.
The key function of TRAFD1 lies in its ability to modulate NF-kB and MAPK signaling pathways, which are crucial for regulating inflammatory responses. The TRAFD1 knockout cell lines allow for the dissection of these pathways by providing a controlled environment to analyze upstream and downstream effects of TRAFD1 loss, making them invaluable tools in elucidating the complexities of immune regulation.
From a scientific perspective, these cell lines are instrumental in various applications, including the study of autoimmune diseases, cancer progression, and therapeutic response. They provide insights into how TRAFD1 may contribute to pathophysiological conditions, thereby offering potential novel targets for intervention.
Compared to other gene knockout models, TRAFD1 Gene Knockout Cell Lines excel in their specificity. They are created using precise gene editing techniques, ensuring a clean and efficient knockout with minimal off-target effects. This robustness allows researchers to achieve reliability in experimental outcomes, thus enhancing reproducibility across studies.
The value of these cell lines is immense for researchers and clinicians looking to understand the intricate roles of TRAFD1 in health and disease. By utilizing these models, users can explore innovative therapeutic strategies and advance knowledge in immunology and cell biology.
Our company specializes in providing high-quality, precision-engineered cellular models, backed by our expertise in molecular biology and genetics. With our TRAFD1 Gene Knockout Cell Lines, researchers gain a powerful toolset to unlock new scientific discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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