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OS9 Knockout Cell Lines

Gene: OS9

Official Full Name: OS9 endoplasmic reticulum lectinprovided by HGNC

Gene Summary: This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04828 OS9 Knockout cell line (HeLa) Human OS9 1:3~1:6 Negative Online Inquiry
KO04829 OS9 Knockout cell line (HCT 116) Human OS9 1:2~1:4 Negative Online Inquiry
KO04830 OS9 Knockout cell line (HEK293) Human OS9 1:3~1:6 Negative Online Inquiry
KO04831 OS9 Knockout cell line (A549) Human OS9 1:3~1:4 Negative Online Inquiry

Background

OS9 Gene Knockout Cell Lines are specifically engineered cellular models that have had the OS9 gene functionally disrupted through targeted gene editing techniques, such as CRISPR-Cas9. OS9, or O-sialoglycoprotein endopeptidase 9, is implicated in various cellular processes, including protein maturation, stress response, and apoptosis. By creating knockout lines of this gene, researchers can study the broader implications of OS9 deficiency on cellular behavior, pathway disruptions, and potential therapeutic targeting.

The key mechanism behind these cell lines lies in their ability to mimic various physiological and pathological states by providing insights into gene function and its associated networks. This genetic alteration allows for a more profound understanding of cellular processes that rely on the OS9 protein, enabling researchers to elucidate its role in diseases such as cancer and neurodegenerative disorders. The OS9 Gene Knockout Cell Lines can be particularly valuable in drug discovery, genetic engineering, and toxicity studies, offering a robust platform for exploring novel therapeutic interventions.

One of the primary advantages of OS9 Gene Knockout Cell Lines is their specificity and reproducibility. Unlike alternative models, which may present variability in genetic background and expression levels, these knockout lines provide a homogeneous and controlled environment, ensuring consistent experimental results. This precision facilitates more reliable conclusions in research findings, enhancing the credibility of outcomes that guide further exploration or clinical applications.

For researchers and clinicians, these cell lines represent an essential tool for advancing our understanding of gene function and its implications in health and disease. Furthermore, the availability of OS9 Gene Knockout Cell Lines underlines your company’s commitment to providing high-quality, cutting-edge research tools that drive innovation in the life sciences field. With robust sourcing and manufacturing processes, your company ensures that these materials meet rigorous scientific standards, making them indispensable assets for any advanced laboratory or clinical setting.

Please note that all services are for research use only. Not intended for any clinical use.

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