Home / OCA2 Knockout Cell Lines

OCA2 Knockout Cell Lines

Gene: OCA2

Official Full Name: OCA2 melanosomal transmembrane proteinprovided by HGNC

Gene Summary: This gene encodes the human homolog of the mouse p (pink-eyed dilution) gene. The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine, which is a precursor to melanin synthesis. It is involved in mammalian pigmentation, where it may control skin color variation and act as a determinant of brown or blue eye color. Mutations in this gene result in type 2 oculocutaneous albinism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04078 OCA2 Knockout cell line (HEK293) Human OCA2 1:3~1:6 Negative Online Inquiry

Background

OCA2 Gene Knockout Cell Lines are genetically modified cells specifically engineered to disrupt the OCA2 gene, which plays a crucial role in pigmentation processes in various organisms, including humans. This product is essential for investigating the biological functions of the OCA2 gene, a key player in melanin synthesis, and its implications in pigmentation disorders, such as oculocutaneous albinism. By utilizing CRISPR-Cas9 or other gene-editing technologies, these cell lines allow researchers to create controlled models for in-depth analysis of gene function and to study the pathological mechanisms that occur when this gene is silenced.

The primary function of OCA2 Gene Knockout Cell Lines lies in their ability to simulate the phenotypic effects of OCA2 deficiency, enabling scientists to explore related cellular pathways and gene interactions. These cell lines serve as a powerful tool for examining the impact of OCA2 mutations on cellular functions such as signal transduction, enzyme activity, and overall genetic expression. Consequently, they play a significant role in advancing our understanding of genetic conditions related to pigmentation, providing a model for therapeutic approaches.

From a scientific perspective, these knockout cell lines are invaluable in both research and clinical settings. They facilitate high-throughput screening for potential drugs targeting pigmentation disorders and allow for the testing of novel genetic therapies. Moreover, the insights gained from studying these cell lines can contribute to the development of diagnostic tools and may eventually lead to more effective treatments.

What sets OCA2 Gene Knockout Cell Lines apart from alternatives is their specificity and reliability. Engineered with precision, they eliminate the OCA2 gene without affecting neighboring genes, providing a cleaner model for experimentation. Additionally, the reproducibility of experimental results and the ability to maintain stability in various culture conditions enhance their utility in diverse research applications.

For researchers and clinicians aiming to unlock the complexities of pigmentation biology and associated disorders, OCA2 Gene Knockout Cell Lines represent a significant asset. Their targeted approach and high level of precision not only save time and resources, but also ensure the integrity of research findings.

Our company, with its robust expertise in genetic engineering and cell line development, is dedicated to delivering high-quality biological products that drive scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.