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MYOZ1 Knockout Cell Lines

Gene: MYOZ1

Official Full Name: myozenin 1provided by HGNC

Gene Summary: The protein encoded by this gene is primarily expressed in the skeletal muscle, and belongs to the myozenin family. Members of this family function as calcineurin-interacting proteins that help tether calcineurin to the sarcomere of cardiac and skeletal muscle. They play an important role in modulation of calcineurin signaling. [provided by RefSeq, Apr 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15942 MYOZ1 Knockout cell line (HEK293) Human MYOZ1 1:3~1:6 Negative Online Inquiry

Background

MYOZ1 Gene Knockout Cell Lines are advanced biological tools specifically engineered to facilitate the in-depth study of MYOZ1 function in various cellular processes. These cell lines have undergone precise genomic editing, which effectively silences the MYOZ1 gene, thereby allowing researchers to observe the resulting phenotypic changes and elucidate the gene's role in muscle biology and disease pathology. The key mechanism behind the knockout functionality involves CRISPR-Cas9 technology, which introduces targeted double-strand breaks in the MYOZ1 gene, leading to its non-functional state through insertion or deletion mutations.

The scientific importance of MYOZ1 Gene Knockout Cell Lines is profound; they serve as critical models for investigating muscle development, hypertrophy, and regeneration, as well as potential implications in myopathies and other muscular disorders. These models are invaluable for preclinical research, drug screening, and the identification of novel therapeutic targets.

What sets these cell lines apart from available alternatives is their high specificity and efficiency in knocking out the MYOZ1 gene, coupled with the robustness of the cellular response observed. Researchers can rely on the consistent performance and reproducibility of results derived from these cell lines, which are validated by comprehensive characterization.

For researchers and clinicians aiming to uncover the nuances of MYOZ1 function, MYOZ1 Gene Knockout Cell Lines represent an exceptional tool that outweighs conventional approaches in terms of precision and versatility. Our commitment to providing high-quality research tools is backed by years of expertise in the field of genomic editing and cell line development, ensuring that our products meet the rigorous demands of modern biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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